statins

The statins wars: Another round and maybe some clarity

7 by / on 11 Jun 2014, / in statins

Don’t prescribe statins to any more people. That’s the clear message from a strongly worded open letter to the head of NICE and to the Health Secretary Jeremy Hunt published today. If you groan at the prospect of yet more confusion over statins, this post might bring a bit of clarity. Please read on.

It’s the latest volley in long running battle about whether cholesterol lowering statins are a good way of cutting the risk of heart attack and death in virtually the entire population with vanishingly small number of effects or whether they don’t actually benefit most people and are quite likely to cause side effects that range from the unpleasant to the deadly.(Read more…)

Eminence based medicine defends the status quo on statins

28 by / on 22 May 2014, / in statins

Last week I was called by a friend who opened the conversation by saying: “So you were wrong about statins.” He was referring to the correction that the British Medical Journal (BMJ) has had to make in two papers that claimed statins have a high level of side effects. But I certainly haven’t recanted and started popping those pills.
Given the huge amount of attention this has attracted, the actual point being “corrected” is remarkably small. It is the kind of thing that would normally be dealt with by publishing a response to the article in the journal. I’ll come to the specifics in a moment but first a bit of context…. (Read more…)

Statin advice from the Wizard of Oz

9 by / on 25 Mar 2014, / in statins

There is a whiff of the Wizard of Oz about the advice on statins that we’ve been getting for years. It comes in the form of ringing pronouncements from behind a curtain that all is well… (Read more…)

SOS: Sanity over Statins – CTT the house of statin secrets

8 by / on 4 Mar 2014, / in statins

Should a professional body, however eminent, be allowed to keep information about the safety of products they are supplying to public hidden so no one else can run tests on them? (Read more…)

SOS: Sanity over Statins – Sssssh Side effects, pharma’s fingers and a cunning plan

0 by / on 4 Mar 2014, / in statins

HealthInsightUK has a number of contributors who are experts in statins. Here three of them – Dr John Briffa, Zoë Harcombe and Aidan Goggins respond to the CTT investigation. They explain why side-effect data is unreliable and disagree about whether it is in the drug companies interest that the risk of side-effects is downplayed or is that part of cunning plan? (Read more…)

Statins: just say no. Sensible reasons why they are stupid medicine

10 by / on 17 Feb 2014, / in statins

Increasingly people are questioning whether it’s worth taking statins, the cholesterol-lowering drugs that are supposed to cut your risk of developing heart disease. We think they are a really bad idea, unless you’ve already got heart disease, and have explained why… (Read more…)

A guided tour around the statin wonderland

20 by / on 16 Dec 2013, / in statins

For years official advice on how best to protect yourself from heart disease has been wonderfully simplistic: high levels of ‘bad’ LDL cholesterol are the major cause, so cut your risk by lowering LDL cholesterol production as much as possible with statin drugs.
Now it turns out that this advice was wrong. Not just according to long-term statin critics but it’s admitted by drug companies themselves. (Read more…)

Cholesterol: I’ve never been wrong so fast or so right

17 by / on 16 Nov 2013, / in statins

Rarely have I been proven wrong quite so fast. After confidently informing the world that the post-statin cholesterol lowering drugs PCSK9 inhibitors would be launched upon an unsuspecting public in the near future, with billion dollar marketing budgets, it seems that I was wrong. Although who knows, I may be wrong about being wrong. (Read more…)

Beware: new cholesterol lowering drugs coming

76 by / on 6 Nov 2013, / in statins

An era is coming to an end. Statins, the world’s most widely prescribed and profitable drugs, have, with the exception Crestor (rosuvastatin), all come off patent and their price has plummeted. Good news for NHS accountants not so good for company profits. (Read more…)

Statin trials: exaggerating benefits and ignoring the harm

1 by / on 30 Oct 2013, / in statins

The ‘Cochrane Collaboration’ is an international collective of researchers whose self-proclaimed role is to provide accurate and robust appraisals of health interventions. The group specialises in ‘meta-analyses’: the grouping together of several similar studies on interventions including drug therapies…

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